No worries, technically some requests to Auth0 may fail depending on the origin from which the call originates, but that would mostly apply in client-side calls coming from web browsers were CORS would be in play like you also mentioned.
However, for calls coming from a backend (Node.js) it would be very unusual for the call to be blocked based on origin; in theory the IP address from your server could be blocked, but that would require really bad behavior like continuously exceeding rate limits so it would not be that common.